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Ligand

NameAM 281
Molecular formulaC21H19Cl2IN4O2
IUPAC name1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-morpholin-4-ylpyrazole-3-carboxamide
Molecular weight557.213
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP5.3
Synonyms202463-68-1
AM-281
BRD-K59419204-001-01-9
GTPL741
NCGC00025009-02
[ Show all ]
Inchi KeyAJFFBPZYXRNAIC-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H19Cl2IN4O2/c1-13-19(21(29)26-27-8-10-30-11-9-27)25-28(18-7-4-15(22)12-17(18)23)20(13)14-2-5-16(24)6-3-14/h2-7,12H,8-11H2,1H3,(H,26,29)
PubChem CID4302962
ChEMBLCHEMBL476833
IUPHAR741
BindingDB50267372
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
6855Cannabinoid receptor 1P20272Cnr1Rattus norvegicus (Rat)473
6856Cannabinoid receptor 1P21554CNR1Homo sapiens (Human)472
6854Cannabinoid receptor 2Q9QZN9Cnr2Rattus norvegicus (Rat)360
6858Cannabinoid receptor 2P34972CNR2Homo sapiens (Human)360
6857G-protein coupled receptor 55Q9Y2T6GPR55Homo sapiens (Human)319

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