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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1081612
Molecular formula	C28H26FN3O2
IUPAC name	[(2S)-4-[3-fluoro-4-(2-methylphenyl)benzoyl]-2-methylpiperazin-1-yl]-(1H-indol-6-yl)methanone
Molecular weight	455.533
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.0
Synonyms	((S)-4-(1H-indole-6-carbonyl)-3-methylpiperazin-1-yl)(2-fluoro-2''-methylbiphenyl-4-yl)methanone BDBM50312787
Inchi Key	AKLCEAZEZRTKJE-IBGZPJMESA-N
Inchi ID	InChI=1S/C28H26FN3O2/c1-18-5-3-4-6-23(18)24-10-9-21(15-25(24)29)27(33)31-13-14-32(19(2)17-31)28(34)22-8-7-20-11-12-30-26(20)16-22/h3-12,15-16,19,30H,13-14,17H2,1-2H3/t19-/m0/s1
PubChem CID	46880725
ChEMBL	CHEMBL1081612
IUPHAR	N/A
BindingDB	50312787
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7646	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
7647	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364

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