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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL42061
Molecular formula	C17H18N4O2
IUPAC name	4-(furan-2-yl)-6-(furan-3-yl)-2-(4-methylpiperazin-1-yl)pyrimidine
Molecular weight	310.357
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.0
Synonyms	2-(4-Methylpiperazin-1-yl)-4-(2-furanyl)-6-(3-furanyl)pyrimidine Pyrimidine, 4-(2-furanyl)-6-(3-furanyl)-2-(4-methyl-1-piperazinyl)- BDBM50289605 CTK0A8077 4-Furan-2-yl-6-furan-3-yl-2-(4-methyl-piperazin-1-yl)-pyrimidine 171115-29-0 DTXSID90440133 [ Show all ]
Inchi Key	AKMGJJTVIPHEOZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18N4O2/c1-20-5-7-21(8-6-20)17-18-14(13-4-10-22-12-13)11-15(19-17)16-3-2-9-23-16/h2-4,9-12H,5-8H2,1H3
PubChem CID	10448104
ChEMBL	CHEMBL42061
IUPHAR	N/A
BindingDB	50289605
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
7686	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
7685	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471

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