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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1774078
Molecular formula	C25H32N4O3
IUPAC name	7-[4-[4-(3,4-dihydro-2H-chromen-5-yl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
Molecular weight	436.556
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.3
Synonyms	BDBM50343275 SCHEMBL5372193 7-(4-(4-(chroman-5-yl)piperazin-1-yl)butoxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
Inchi Key	ANCFDBAFLRCWEK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H32N4O3/c30-23-10-8-19-9-11-24(27-25(19)26-23)32-17-2-1-12-28-13-15-29(16-14-28)21-6-3-7-22-20(21)5-4-18-31-22/h3,6-7,9,11H,1-2,4-5,8,10,12-18H2,(H,26,27,30)
PubChem CID	21073788
ChEMBL	CHEMBL1774078
IUPHAR	N/A
BindingDB	50343275
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9434	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
9435	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
9433	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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