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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	GSK163090
Molecular formula	C25H29N5O
IUPAC name	1-[3-[2-[4-(2-methylquinolin-5-yl)piperazin-1-yl]ethyl]phenyl]imidazolidin-2-one
Molecular weight	415.541
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.4
Synonyms	AKOS030526918 EX-A1027 ZINC34451922 1-(3-(2-(4-(2-Methyl-5-quinolinyl)-1-piperazinyl)ethyl)phenyl)-2-imidazolidinone BDBM50333015 GSK-163090;GSK 163090 7XI927X82B CS-5315 SCHEMBL2881345 ANGUXJDGJCHGOG-UHFFFAOYSA-N GSK 163090 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone 844903-58-8 DTXSID30233480 UNII-7XI927X82B BCP16941 GSK-163090 1-[3-[2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl]phenyl]-2-imidazolidinone CHEMBL1631540 HY-14348 [ Show all ]
Inchi Key	ANGUXJDGJCHGOG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29N5O/c1-19-8-9-22-23(27-19)6-3-7-24(22)29-16-14-28(15-17-29)12-10-20-4-2-5-21(18-20)30-13-11-26-25(30)31/h2-9,18H,10-17H2,1H3,(H,26,31)
PubChem CID	11292933
ChEMBL	CHEMBL1631540
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
9546	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
9543	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
9545	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
9550	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
9541	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
9549	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
9544	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
9542	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
9547	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
9552	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
9551	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
9548	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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