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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	5-(2,4-dimethoxyphenyl)-3-hydroxy-1-(2-morpholin-4-ylethyl)-4-(thien-2-ylcarbonyl)-1,5-dihydro-2H-pyrrol-2-one
Molecular formula	C23H26N2O6S
IUPAC name	2-(2,4-dimethoxyphenyl)-4-hydroxy-1-(2-morpholin-4-ylethyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one
Molecular weight	458.529
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	2.6
Synonyms	MLS001196801 SMR000555943 HMS2866G24 AKOS001650673 MolPort-007-564-561 CHEMBL1366441 SR-01000486783 MCULE-5528419929 AKOS021997912 Oprea1_350696 EU-0077458 SR-01000486783-1 [ Show all ]
Inchi Key	AOGPOKSQGHHQRG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26N2O6S/c1-29-15-5-6-16(17(14-15)30-2)20-19(21(26)18-4-3-13-32-18)22(27)23(28)25(20)8-7-24-9-11-31-12-10-24/h3-6,13-14,20,27H,7-12H2,1-2H3
PubChem CID	15996528
ChEMBL	CHEMBL1366441
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10223	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350

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