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Ligand

NameCHEMBL584343
Molecular formulaC18H23ClN4O2
IUPAC name5-chloro-1-[(1R)-1-cyclopropylpropyl]-3-[(6-methoxy-2,5-dimethylpyridin-3-yl)amino]pyrazin-2-one
Molecular weight362.858
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP3.4
SynonymsBDBM50300136
SCHEMBL12410258
(R)-5-Chloro-1-(1-cyclopropylpropyl)-3-(6-methoxy-2,5-dimethylpyridin-3-ylamino)pyrazin-2(1H)-one
Inchi KeyAOQNUAUZFQJNHU-CQSZACIVSA-N
Inchi IDInChI=1S/C18H23ClN4O2/c1-5-14(12-6-7-12)23-9-15(19)22-16(18(23)24)21-13-8-10(2)17(25-4)20-11(13)3/h8-9,12,14H,5-7H2,1-4H3,(H,21,22)/t14-/m1/s1
PubChem CID44596809
ChEMBLCHEMBL584343
IUPHARN/A
BindingDB50300136
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 1
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GLASS IDNameUniProtGeneSpeciesLength
10517Corticotropin-releasing factor receptor 1P35353Crhr1Rattus norvegicus (Rat)415

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