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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL494982
Molecular formula	C17H21N3O
IUPAC name	2-[3-(1H-imidazol-5-ylmethyl)phenyl]-4,4,6-trimethyl-5,6-dihydro-1,3-oxazine
Molecular weight	283.375
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.9
Synonyms	4-Benzyl-1H-imidazole derivative, 26 2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,4,6-trimethyl-5,6-dihydro-4H-1,3-oxazine BDBM22548
Inchi Key	APQJKSFOISLQFF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21N3O/c1-12-9-17(2,3)20-16(21-12)14-6-4-5-13(7-14)8-15-10-18-11-19-15/h4-7,10-12H,8-9H2,1-3H3,(H,18,19)
PubChem CID	24825522
ChEMBL	CHEMBL494982
IUPHAR	N/A
BindingDB	22548
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11248	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
11245	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
11244	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445
11246	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
11247	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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