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Ligand

NameLEXIPAFANT
Molecular formulaC23H30N4O4S
IUPAC nameethyl (2S)-4-methyl-2-[methyl-[4-[(2-methylimidazo[4,5-c]pyridin-1-yl)methyl]phenyl]sulfonylamino]pentanoate
Molecular weight458.577
Hydrogen bond acceptor7
Hydrogen bond donor0
XlogP3.5
Synonyms(S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-benzenesulfonyl]-amino}-pentanoic acid ethyl ester
L-Leucine, N-methyl-N-((4-((2-methyl-1H-imidazo(4,5-c)pyridin-1-yl)ethyl)phenyl)sulfonyl)-, ethyl ester
D05LYN
Lexipafant [USAN:INN:BAN]
BDBM50048485
[ Show all ]
Inchi KeyAQRXDPFOYJSPMP-QFIPXVFZSA-N
Inchi IDInChI=1S/C23H30N4O4S/c1-6-31-23(28)22(13-16(2)3)26(5)32(29,30)19-9-7-18(8-10-19)15-27-17(4)25-20-14-24-12-11-21(20)27/h7-12,14,16,22H,6,13,15H2,1-5H3/t22-/m0/s1
PubChem CID9804204
ChEMBLCHEMBL322832
IUPHARN/A
BindingDB50048485
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
12047Platelet-activating factor receptorP25105PTAFRHomo sapiens (Human)342
12048Platelet-activating factor receptorP21556PTAFRCavia porcellus (Guinea pig)342

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