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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL75108
Molecular formula	C37H38F2N2O6S
IUPAC name	(5,7-difluoronaphthalen-1-yl)-[4-[4-[2-[4-(4-methoxyphenyl)sulfonylphenyl]-1,3-dioxolan-2-yl]piperidin-1-yl]piperidin-1-yl]methanone
Molecular weight	676.776
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	5.9
Synonyms	(5,7-Difluoro-naphthalen-1-yl)-(4-{2-[4-(4-methoxy-benzenesulfonyl)-phenyl]-[1,3]dioxolan-2-yl}-[1,4'']bipiperidinyl-1''-yl)-methanone BDBM50103772 1'-(5,7-Difluoro-1-naphthylcarbonyl)-4-[2-[4-(4-methoxyphenylsulfonyl)phenyl]-1,3-dioxolane-2-yl]-1,4'-bi[piperidine]
Inchi Key	AQTWXHKJEFVDRR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C37H38F2N2O6S/c1-45-29-7-11-31(12-8-29)48(43,44)30-9-5-25(6-10-30)37(46-21-22-47-37)26-13-17-40(18-14-26)28-15-19-41(20-16-28)36(42)33-4-2-3-32-34(33)23-27(38)24-35(32)39/h2-12,23-24,26,28H,13-22H2,1H3
PubChem CID	44314564
ChEMBL	CHEMBL75108
IUPHAR	N/A
BindingDB	50103772
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12096	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466

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