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Ligand

NameCHEMBL74144
Molecular formulaC35H34FN5O6S
IUPAC name3-methylbutyl N-[2-[4-[[2-ethyl-4-oxo-6-(pyridine-2-carbonylamino)quinazolin-3-yl]methyl]-3-fluorophenyl]phenyl]sulfonylcarbamate
Molecular weight671.744
Hydrogen bond acceptor9
Hydrogen bond donor2
XlogP5.5
Synonyms2-ethyl-3-(3-fluoro-2''-(3-methyl-butyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(2-pyridylcarbonylamino)-3H-quinazolin-4-one
BDBM50283311
Inchi KeyARHOSTGQGGKVFS-UHFFFAOYSA-N
Inchi IDInChI=1S/C35H34FN5O6S/c1-4-32-39-29-15-14-25(38-33(42)30-10-7-8-17-37-30)20-27(29)34(43)41(32)21-24-13-12-23(19-28(24)36)26-9-5-6-11-31(26)48(45,46)40-35(44)47-18-16-22(2)3/h5-15,17,19-20,22H,4,16,18,21H2,1-3H3,(H,38,42)(H,40,44)
PubChem CID44315059
ChEMBLCHEMBL74144
IUPHARN/A
BindingDB50283311
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
12482Type-1 angiotensin II receptorP30556AGTR1Homo sapiens (Human)359
12483Type-1 angiotensin II receptorP34976AGTR1Oryctolagus cuniculus (Rabbit)359
12481Type-2 angiotensin II receptorP35351Agtr2Rattus norvegicus (Rat)363
12484Type-2 angiotensin II receptorP50052AGTR2Homo sapiens (Human)363

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