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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL74144
Molecular formula	C35H34FN5O6S
IUPAC name	3-methylbutyl N-[2-[4-[[2-ethyl-4-oxo-6-(pyridine-2-carbonylamino)quinazolin-3-yl]methyl]-3-fluorophenyl]phenyl]sulfonylcarbamate
Molecular weight	671.744
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	5.5
Synonyms	BDBM50283311 2-ethyl-3-(3-fluoro-2''-(3-methyl-butyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(2-pyridylcarbonylamino)-3H-quinazolin-4-one
Inchi Key	ARHOSTGQGGKVFS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C35H34FN5O6S/c1-4-32-39-29-15-14-25(38-33(42)30-10-7-8-17-37-30)20-27(29)34(43)41(32)21-24-13-12-23(19-28(24)36)26-9-5-6-11-31(26)48(45,46)40-35(44)47-18-16-22(2)3/h5-15,17,19-20,22H,4,16,18,21H2,1-3H3,(H,38,42)(H,40,44)
PubChem CID	44315059
ChEMBL	CHEMBL74144
IUPHAR	N/A
BindingDB	50283311
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12482	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
12483	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
12481	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363
12484	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363

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