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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2370965
Molecular formula	C81H107N19O15
IUPAC name	(3S)-3-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]acetyl]amino]-2-methyl-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-oxobutanoic acid
Molecular weight	1586.86
Hydrogen bond acceptor	18
Hydrogen bond donor	19
XlogP	0.9
Synonyms	BDBM50134957 CHEMBL441938 H-Tyr-Val-Nle-Gly-MePhe-Phe-Arg-D-Nal(2)-Asp-Arg-Phe-Gly-NH2
Inchi Key	ARYIUPJTXJSVAP-NYKBICRUSA-N
Inchi ID	InChI=1S/C81H107N19O15/c1-5-6-28-58(94-77(114)68(48(2)3)99-69(106)57(82)40-51-32-35-56(101)36-33-51)70(107)91-47-66(103)100-81(4,45-52-24-14-9-15-25-52)78(115)98-63(42-50-22-12-8-13-23-50)75(112)92-60(30-19-38-89-80(86)87)73(110)96-62(43-53-31-34-54-26-16-17-27-55(54)39-53)74(111)97-64(44-67(104)105)76(113)93-59(29-18-37-88-79(84)85)72(109)95-61(71(108)90-46-65(83)102)41-49-20-10-7-11-21-49/h7-17,20-27,31-36,39,48,57-64,68,101H,5-6,18-19,28-30,37-38,40-47,82H2,1-4H3,(H2,83,102)(H,90,108)(H,91,107)(H,92,112)(H,93,113)(H,94,114)(H,95,109)(H,96,110)(H,97,111)(H,98,115)(H,99,106)(H,100,103)(H,104,105)(H4,84,85,88)(H4,86,87,89)/t57-,58-,59-,60-,61-,62+,63-,64-,68-,81-/m0/s1
PubChem CID	73353101
ChEMBL	CHEMBL2370965
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12893	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
12891	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
12892	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325

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