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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL142962
Molecular formula	C20H20N4O
IUPAC name	2-(furan-2-yl)-5,6-dimethyl-7-[(1R)-1-phenylethyl]pyrrolo[2,3-d]pyrimidin-4-amine
Molecular weight	332.407
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.8
Synonyms	2-Furan-2-yl-5,6-dimethyl-7-(1-phenyl-ethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine 2-(2-Furyl)-5,6-dimethyl-7-[(R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidine-4-amine BDBM50094599
Inchi Key	ATJYGASFPFEOJQ-CQSZACIVSA-N
Inchi ID	InChI=1S/C20H20N4O/c1-12-13(2)24(14(3)15-8-5-4-6-9-15)20-17(12)18(21)22-19(23-20)16-10-7-11-25-16/h4-11,14H,1-3H3,(H2,21,22,23)/t14-/m1/s1
PubChem CID	10592691
ChEMBL	CHEMBL142962
IUPHAR	N/A
BindingDB	50094599
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14022	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
14021	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410

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