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Ligand

Namespiropiperidine analogue, 39
Molecular formulaC33H38Cl2N4O
IUPAC name8-[bis(2-chlorophenyl)methyl]-1-phenyl-3-(2-piperidin-1-ylethyl)-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight577.594
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP7.2
Synonyms8-[bis(2-chlorophenyl)methyl]-1-phenyl-3-[2-(piperidin-1-yl)ethyl]-1,3,8-triazaspiro[4.5]decan-4-one
CHEMBL464192
BDBM26918
Inchi KeyAWCUCKNTBFFHCS-UHFFFAOYSA-N
Inchi IDInChI=1S/C33H38Cl2N4O/c34-29-15-7-5-13-27(29)31(28-14-6-8-16-30(28)35)37-21-17-33(18-22-37)32(40)38(24-23-36-19-9-2-10-20-36)25-39(33)26-11-3-1-4-12-26/h1,3-8,11-16,31H,2,9-10,17-25H2
PubChem CID25190597
ChEMBLCHEMBL464192
IUPHARN/A
BindingDB26918
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 4
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
15885Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
15887Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
15888Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
15886Nociceptin receptorP41146OPRL1Homo sapiens (Human)370

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