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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	spiropiperidine analogue, 39
Molecular formula	C33H38Cl2N4O
IUPAC name	8-[bis(2-chlorophenyl)methyl]-1-phenyl-3-(2-piperidin-1-ylethyl)-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	577.594
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	7.2
Synonyms	8-[bis(2-chlorophenyl)methyl]-1-phenyl-3-[2-(piperidin-1-yl)ethyl]-1,3,8-triazaspiro[4.5]decan-4-one CHEMBL464192 BDBM26918
Inchi Key	AWCUCKNTBFFHCS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H38Cl2N4O/c34-29-15-7-5-13-27(29)31(28-14-6-8-16-30(28)35)37-21-17-33(18-22-37)32(40)38(24-23-36-19-9-2-10-20-36)25-39(33)26-11-3-1-4-12-26/h1,3-8,11-16,31H,2,9-10,17-25H2
PubChem CID	25190597
ChEMBL	CHEMBL464192
IUPHAR	N/A
BindingDB	26918
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15885	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
15887	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
15888	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
15886	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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