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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1915866
Molecular formula	C25H20Cl2F2N2O5
IUPAC name	2-[4-chloro-3-[[2-chloro-4-[[(2S)-4-methyl-2,3-dihydro-1,4-benzoxazin-2-yl]methoxy]benzoyl]amino]phenyl]-2,2-difluoroacetic acid
Molecular weight	537.341
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.8
Synonyms	SCHEMBL730099 BDBM50357636
Inchi Key	AWGFVNBSZWQCDL-INIZCTEOSA-N
Inchi ID	InChI=1S/C25H20Cl2F2N2O5/c1-31-12-16(36-22-5-3-2-4-21(22)31)13-35-15-7-8-17(19(27)11-15)23(32)30-20-10-14(6-9-18(20)26)25(28,29)24(33)34/h2-11,16H,12-13H2,1H3,(H,30,32)(H,33,34)/t16-/m0/s1
PubChem CID	57401554
ChEMBL	CHEMBL1915866
IUPHAR	N/A
BindingDB	50357636
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15993	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
15994	Prostaglandin D2 receptor	P70263	Ptgdr	Mus musculus (Mouse)	357

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