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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL187071
Molecular formula	C22H23F3N8O
IUPAC name	2-(furan-2-yl)-7-N-methyl-7-N-[2-[4-(2,4,6-trifluorophenyl)piperazin-1-yl]ethyl]-[1,2,4]triazolo[1,5-c]pyrimidine-5,7-diamine
Molecular weight	472.476
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	2.9
Synonyms	2-Furan-2-yl-N7-methyl-N7-{2-[4-(2,4,6-trifluoro-phenyl)-piperazin-1-yl]-ethyl}-[1,2,4]triazolo[1,5-c]pyrimidine-5,7-diamine BDBM50152242 SCHEMBL5654046
Inchi Key	AWZBLJMDHCKOOF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H23F3N8O/c1-30(18-13-19-27-21(17-3-2-10-34-17)29-33(19)22(26)28-18)4-5-31-6-8-32(9-7-31)20-15(24)11-14(23)12-16(20)25/h2-3,10-13H,4-9H2,1H3,(H2,26,28)
PubChem CID	11351928
ChEMBL	CHEMBL187071
IUPHAR	N/A
BindingDB	50152242
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16472	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
16471	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410

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