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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL363660
Molecular formula	C22H24F2N8O
IUPAC name	7-N-[2-[4-(2,4-difluorophenyl)piperazin-1-yl]ethyl]-2-(furan-2-yl)-7-N-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-5,7-diamine
Molecular weight	454.486
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	2.8
Synonyms	SCHEMBL6009836 BDBM50152233 N7-{2-[4-(2,4-Difluoro-phenyl)-piperazin-1-yl]-ethyl}-2-furan-2-yl-N7-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-5,7-diamine N7-(2-(4-(2,4-difluorophenyl)piperazin-1-yl)ethyl)-2-(furan-2-yl)-N7-methyl-[1,2,4]triazolo[1,5-c]pyrimidine-5,7-diamine
Inchi Key	AYDUITGMILRLFK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24F2N8O/c1-29(6-7-30-8-10-31(11-9-30)17-5-4-15(23)13-16(17)24)19-14-20-26-21(18-3-2-12-33-18)28-32(20)22(25)27-19/h2-5,12-14H,6-11H2,1H3,(H2,25,27)
PubChem CID	11476550
ChEMBL	CHEMBL363660
IUPHAR	N/A
BindingDB	50152233
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17368	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
17367	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
17369	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410

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