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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000241362
Molecular formula	C24H24N2O6S
IUPAC name	[2-(4-acetyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-oxoethyl] 3-[methyl(phenyl)sulfamoyl]benzoate
Molecular weight	468.524
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.5
Synonyms	AC1M2Q7N MolPort-004-042-599 CHEMBL1575549 ZINC2658759 2-(4-acetyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-oxoethyl 3-[methyl(phenyl)sulfamoyl]benzoate MLS000393509 AKOS033646768 HMS2580O11 [2-(4-acetyl-3,5-dimethyl-1H-pyrrol-2-yl)-2-oxoethyl] 3-[methyl(phenyl)sulfamoyl]benzoate 753475-95-5 MLS003915044 Z18869703 MCULE-9325777118 [ Show all ]
Inchi Key	AYEYMGXVPYEVOU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24N2O6S/c1-15-22(17(3)27)16(2)25-23(15)21(28)14-32-24(29)18-9-8-12-20(13-18)33(30,31)26(4)19-10-6-5-7-11-19/h5-13,25H,14H2,1-4H3
PubChem CID	2122530
ChEMBL	CHEMBL1575549
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17395	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
465017	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
17394	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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