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Ligand

NameCHEMBL2165195
Molecular formulaC19H23ClFN3O3
IUPAC name5-chloro-1-[(1R)-1-cyclopropyl-2-methoxyethyl]-3-[4-(fluoromethoxy)-2,5-dimethylanilino]pyrazin-2-one
Molecular weight395.859
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP3.5
SynonymsBDBM50395833
Inchi KeyAYICDFKLBCUUCO-HNNXBMFYSA-N
Inchi IDInChI=1S/C19H23ClFN3O3/c1-11-7-16(27-10-21)12(2)6-14(11)22-18-19(25)24(8-17(20)23-18)15(9-26-3)13-4-5-13/h6-8,13,15H,4-5,9-10H2,1-3H3,(H,22,23)/t15-/m0/s1
PubChem CID71455126
ChEMBLCHEMBL2165195
IUPHARN/A
BindingDB50395833
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 1
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GLASS IDNameUniProtGeneSpeciesLength
17480Corticotropin-releasing factor receptor 1P35353Crhr1Rattus norvegicus (Rat)415

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