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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL383548
Molecular formula	C20H20Cl2N6O5
IUPAC name	(2S,3S,4R,5R)-5-[6-[[2-(2,4-dichlorophenyl)acetyl]amino]purin-9-yl]-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
Molecular weight	495.317
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	1.2
Synonyms	(2S,3S,4R,5R)-5-(6-(2-(2,4-dichlorophenyl)acetamido)-9H-purin-9-yl)-N-ethyl-3,4-dihydroxy-tetrahydrofuran-2-carboxamide BDBM50179038 N-(alpha-Oxo-2,4-dichlorophenethyl)-5'-(ethylamino)-5'-oxo-5'-deoxyadenosine
Inchi Key	AYIOONPUFNVWIY-KSVNGYGVSA-N
Inchi ID	InChI=1S/C20H20Cl2N6O5/c1-2-23-19(32)16-14(30)15(31)20(33-16)28-8-26-13-17(24-7-25-18(13)28)27-12(29)5-9-3-4-10(21)6-11(9)22/h3-4,6-8,14-16,20,30-31H,2,5H2,1H3,(H,23,32)(H,24,25,27,29)/t14-,15+,16-,20+/m0/s1
PubChem CID	10577168
ChEMBL	CHEMBL383548
IUPHAR	N/A
BindingDB	50179038
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17485	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
17484	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
17483	Adenosine receptor A3	P28647	Adora3	Rattus norvegicus (Rat)	320

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