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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1775170
Molecular formula	C20H23N5O5S
IUPAC name	ethyl 4-[1-(4-methylsulfonylphenyl)pyrazolo[3,4-d]pyrimidin-4-yl]oxypiperidine-1-carboxylate
Molecular weight	445.494
Hydrogen bond acceptor	8
Hydrogen bond donor	0
XlogP	2.2
Synonyms	AYMXTWMJUAASDF-UHFFFAOYSA-N 142941-EP2287165A2 4-[1-(4-Methanesulfonyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy]-piperidine-1-carboxylic acid ethyl ester BDBM50343450 142941-EP2287166A2 ethyl 4-(1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate 142941-EP2292620A2 SCHEMBL389690 [ Show all ]
Inchi Key	AYMXTWMJUAASDF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23N5O5S/c1-3-29-20(26)24-10-8-15(9-11-24)30-19-17-12-23-25(18(17)21-13-22-19)14-4-6-16(7-5-14)31(2,27)28/h4-7,12-13,15H,3,8-11H2,1-2H3
PubChem CID	53630415
ChEMBL	CHEMBL1775170
IUPHAR	N/A
BindingDB	50343450
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17599	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468
17600	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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