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Ligand

Name845808-35-7
Molecular formulaC25H27N3O5
IUPAC name4-hydroxy-1-(3-imidazol-1-ylpropyl)-3-(5-methylfuran-2-carbonyl)-2-(4-propan-2-yloxyphenyl)-2H-pyrrol-5-one
Molecular weight449.507
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP3.6
SynonymsMLS001074033
AKOS016304012
VU0605623-1
3-hydroxy-1-(3-imidazolylpropyl)-4-[(5-methyl(2-furyl))carbonyl]-5-[4-(methyle thoxy)phenyl]-3-pyrrolin-2-one
F3226-1855
[ Show all ]
Inchi KeyAZXVHGLYSPMUHG-UHFFFAOYSA-N
Inchi IDInChI=1S/C25H27N3O5/c1-16(2)32-19-8-6-18(7-9-19)22-21(23(29)20-10-5-17(3)33-20)24(30)25(31)28(22)13-4-12-27-14-11-26-15-27/h5-11,14-16,22,30H,4,12-13H2,1-3H3
PubChem CID663879
ChEMBLCHEMBL1374204
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
465150fMet-Leu-Phe receptorP21462FPR1Homo sapiens (Human)350
18577Neuropeptide S receptorQ6W5P4NPSR1Homo sapiens (Human)371
18578Relaxin receptor 1Q9HBX9RXFP1Homo sapiens (Human)757

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