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Ligand

NameDG-041
Molecular formulaC23H15Cl4FN2O3S2
IUPAC name(E)-3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methylindol-7-yl]-N-(4,5-dichlorothiophen-2-yl)sulfonylprop-2-enamide
Molecular weight592.302
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP7.8
SynonymsCHEMBL565591
SB16533
(2e)-3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methyl-1h-indol-7-yl]-n-[(4,5-dichloro-2-thienyl)sulfonyl]-2-propenamide
1844425CLP
AKOS032962881
[ Show all ]
Inchi KeyBFBTVZNKWXWKNZ-HWKANZROSA-N
Inchi IDInChI=1S/C23H15Cl4FN2O3S2/c1-12-10-30(11-14-2-4-15(24)7-18(14)25)22-13(6-16(28)8-17(12)22)3-5-20(31)29-35(32,33)21-9-19(26)23(27)34-21/h2-10H,11H2,1H3,(H,29,31)/b5-3+
PubChem CID11296282
ChEMBLCHEMBL565591
IUPHAR5822
BindingDB50303662
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
22145Prostacyclin receptorP43119PTGIRHomo sapiens (Human)386
22148Prostaglandin E2 receptor EP1 subtypeP34995PTGER1Homo sapiens (Human)402
22149Prostaglandin E2 receptor EP2 subtypeP43116PTGER2Homo sapiens (Human)358
22144Prostaglandin E2 receptor EP3 subtypeP43115PTGER3Homo sapiens (Human)390
22147Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
22146Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488

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