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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CGP-57698
Molecular formula	C24H25FN2O4
IUPAC name	2,2-diethyl-4-[3-[(7-fluoroquinolin-2-yl)methoxy]anilino]-4-oxobutanoic acid
Molecular weight	424.472
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.0
Synonyms	BFNAFTJCDGWFMQ-UHFFFAOYSA-N SCHEMBL8179248 2,2-Diethyl-N-[3-(7-fluoro-quinolin-2-ylmethoxy)-phenyl]-succinamic acid D04CZQ Butanoic acid, 2,2-diethyl-4-((3-((7-fluoro-2-quinolinyl)methoxy)phenyl)amino)-4-oxo- 4-[3-(7-fluoro-2-quinolinyl-methoxy)phenyl-amino]-2,2-diethyl-4-oxo-buta-noic acid BDBM50068974 L015501 CGP 57698 168082-74-4 4-[3-(7-fluoro-2-quinolinylmethoxy)phenylamino]-2,2-diethyl-4-oxobutanoic acid CHEMBL178221 [ Show all ]
Inchi Key	BFNAFTJCDGWFMQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25FN2O4/c1-3-24(4-2,23(29)30)14-22(28)27-18-6-5-7-20(13-18)31-15-19-11-9-16-8-10-17(25)12-21(16)26-19/h5-13H,3-4,14-15H2,1-2H3,(H,27,28)(H,29,30)
PubChem CID	9888588
ChEMBL	CHEMBL178221
IUPHAR	N/A
BindingDB	50068974
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22447	Cysteinyl leukotriene receptor 1	Q2NNR5	CYSLTR1	Cavia porcellus (Guinea pig)	340

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