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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3298463
Molecular formula	C21H16F2N2O2
IUPAC name	2-[(3-fluorophenoxy)methyl]-6-(4-fluorophenyl)-7,8-dihydro-1,6-naphthyridin-5-one
Molecular weight	366.368
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.6
Synonyms	BHCSFEWFNXLJEJ-UHFFFAOYSA-N SCHEMBL10008695 BDBM50022820 2-((3-fluorophenoxy)methyl)-6-(4-fluorophenyl)-7,8-dihydro-1,6-naphthyridin-5(6H)-one
Inchi Key	BHCSFEWFNXLJEJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H16F2N2O2/c22-14-4-7-17(8-5-14)25-11-10-20-19(21(25)26)9-6-16(24-20)13-27-18-3-1-2-15(23)12-18/h1-9,12H,10-11,13H2
PubChem CID	68008456
ChEMBL	CHEMBL3298463
IUPHAR	N/A
BindingDB	50022820
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23637	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
23636	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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