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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL1833847
Molecular formula	C24H26N6
IUPAC name	2-[1-(6-benzyl-4,5-dimethylpyridazin-3-yl)piperidin-4-yl]-1H-imidazo[4,5-b]pyridine
Molecular weight	398.514
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.1
Synonyms	CHEMBL3958236 BICVVNYZNHJZPZ-UHFFFAOYSA-N 2-[1-(6-benzyl-4,5-dimethyl-pyridazin-3-yl)-piperidin-4-yl]-1H-imidazo[4,5-b]pyridine
Inchi Key	BICVVNYZNHJZPZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26N6/c1-16-17(2)24(29-28-21(16)15-18-7-4-3-5-8-18)30-13-10-19(11-14-30)22-26-20-9-6-12-25-23(20)27-22/h3-9,12,19H,10-11,13-15H2,1-2H3,(H,25,26,27)
PubChem CID	67177962
ChEMBL	CHEMBL3958236
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
536608	Smoothened homolog	P56726	Smo	Mus musculus (Mouse)	793
536609	Smoothened homolog	Q99835	SMO	Homo sapiens (Human)	787

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