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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Nortopsentin A
Molecular formula	C19H12Br2N4
IUPAC name	6-bromo-3-[2-(6-bromo-1H-indol-3-yl)-1H-imidazol-5-yl]-1H-indole
Molecular weight	456.141
Hydrogen bond acceptor	1
Hydrogen bond donor	3
XlogP	5.0
Synonyms	AC1L44WZ SCHEMBL8616377 3,3'-Imidazole-2,4-diylbis(6-bromoindole) 6-bromo-3-[2-(6-bromo-1H-indol-3-yl)-1H-imidazol-5-yl]-1H-indole 134029-43-9 BDBM50287723 CHEMBL302637 6-bromo-3-[4-(6-bromo-1H-3-indolyl)-1H-2-imidazolyl]-1H-indole SCHEMBL17243838 1H-Indole, 3,3'-(1H-imidazole-2,4-diyl)bis(6-bromo- BIGUXWQKCPFOAH-UHFFFAOYSA-N 6-bromo-3-[2-(6-bromo-1H-indol-3-yl)-1H-imidazol-4-yl]-1H-indole DTXSID50158464 [ Show all ]
Inchi Key	BIGUXWQKCPFOAH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H12Br2N4/c20-10-1-3-12-14(7-22-16(12)5-10)18-9-24-19(25-18)15-8-23-17-6-11(21)2-4-13(15)17/h1-9,22-23H,(H,24,25)
PubChem CID	179268
ChEMBL	CHEMBL302637
IUPHAR	N/A
BindingDB	50287723
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24428	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
24429	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520

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