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Ligand

NameCHEMBL460093
Molecular formulaC28H29Cl2FN2
IUPAC name[(1S,5S)-8-[bis(2-chlorophenyl)methyl]-3-[(4-fluorophenyl)methyl]-8-azabicyclo[3.2.1]octan-3-yl]methanamine
Molecular weight483.452
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP7.0
SynonymsBDBM50245974
(rel)-(3-(4-fluorobenzyl)-8-(bis(2-chlorophenyl)methyl)-8-aza-bicyclo[3.2.1]octan-3-yl)methanamine
Inchi KeyBJUFPJMTZSDVBA-VXKWHMMOSA-N
Inchi IDInChI=1S/C28H29Cl2FN2/c29-25-7-3-1-5-23(25)27(24-6-2-4-8-26(24)30)33-21-13-14-22(33)17-28(16-21,18-32)15-19-9-11-20(31)12-10-19/h1-12,21-22,27H,13-18,32H2/t21-,22-/m0/s1
PubChem CID44562786
ChEMBLN/A
IUPHARN/A
BindingDB50245974
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
25456Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
25455Nociceptin receptorP41146OPRL1Homo sapiens (Human)370

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