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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL243953
Molecular formula	C30H43N3O
IUPAC name	6-[4-(2-tert-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Molecular weight	461.694
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.1
Synonyms	6-[4-(2-tert-butylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide BDBM21382 Piperazinehexanamide derivative, 20
Inchi Key	BLCHSWWAUDRFLL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H43N3O/c1-30(2,3)26-15-8-9-17-28(26)33-22-20-32(21-23-33)19-10-4-5-18-29(34)31-27-16-11-13-24-12-6-7-14-25(24)27/h6-9,12,14-15,17,27H,4-5,10-11,13,16,18-23H2,1-3H3,(H,31,34)
PubChem CID	24768519
ChEMBL	CHEMBL243953
IUPHAR	N/A
BindingDB	21382
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
26392	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
26391	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
26393	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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