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Ligand

Namecorynanthine
Molecular formulaC21H26N2O3
IUPAC namemethyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Molecular weight354.45
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP2.9
Synonyms(1S,2S,4aR,13bS,14aS)-2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2'',3'':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester
AKOS024282584
BSPBio_000396
EINECS 207-590-0
methyl (1S,15R,18S,19S,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate
[ Show all ]
Inchi KeyBLGXFZZNTVWLAY-DKJBZYCGSA-N
Inchi IDInChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19-/m0/s1
PubChem CID92766
ChEMBLCHEMBL31410
IUPHARN/A
BindingDB50027058
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
26563Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
26566Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
26570Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
26564Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
26567Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
26568Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
26565Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
26569Thyrotropin receptorP16473TSHRHomo sapiens (Human)764

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