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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2113149
Molecular formula	C35H42ClN5O2
IUPAC name	(3R)-N-[(2R)-3-(4-chlorophenyl)-1-[4-[7-(dimethylamino)-5,6,7,8-tetrahydronaphthalen-1-yl]piperazin-1-yl]-1-oxopropan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Molecular weight	600.204
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.2
Synonyms	SCHEMBL14591448
Inchi Key	BOSMDIPMRDHNDU-HMDBZMABSA-N
Inchi ID	InChI=1S/C35H42ClN5O2/c1-39(2)29-15-12-25-8-5-9-33(30(25)22-29)40-16-18-41(19-17-40)35(43)32(20-24-10-13-28(36)14-11-24)38-34(42)31-21-26-6-3-4-7-27(26)23-37-31/h3-11,13-14,29,31-32,37H,12,15-23H2,1-2H3,(H,38,42)/t29?,31-,32-/m1/s1
PubChem CID	58777892
ChEMBL	CHEMBL2113149
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29092	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
29095	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
29094	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325
29093	Melanocyte-stimulating hormone receptor	Q01726	MC1R	Homo sapiens (Human)	317

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