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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1774224
Molecular formula	C21H23F3N4
IUPAC name	1-methyl-2-[[(2R,4R)-2-methyl-4-[4-(trifluoromethyl)phenyl]piperidin-1-yl]methyl]imidazo[4,5-b]pyridine
Molecular weight	388.438
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.1
Synonyms	cis-1-methyl-2-(((2R,4R)-2-methyl-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)methyl)-1H-imidazo[4,5-b]pyridine BDBM50343316
Inchi Key	BOZVHERQYJVRDG-GDBMZVCRSA-N
Inchi ID	InChI=1S/C21H23F3N4/c1-14-12-16(15-5-7-17(8-6-15)21(22,23)24)9-11-28(14)13-19-26-20-18(27(19)2)4-3-10-25-20/h3-8,10,14,16H,9,11-13H2,1-2H3/t14-,16-/m1/s1
PubChem CID	51356571
ChEMBL	CHEMBL1774224
IUPHAR	N/A
BindingDB	50343316
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29324	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
29326	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558155	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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