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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL106065
Molecular formula	C33H34F3N5O3
IUPAC name	N-[(1-pyridin-2-ylcyclohexyl)methyl]-3-[[4-(trifluoromethoxy)phenyl]carbamoylamino]-1,2,4,9-tetrahydrocarbazole-3-carboxamide
Molecular weight	605.662
Hydrogen bond acceptor	7
Hydrogen bond donor	4
XlogP	6.7
Synonyms	BDBM50147037 3-[3-(4-Trifluoromethoxy-phenyl)-ureido]-2,3,4,9-tetrahydro-1H-carbazole-3-carboxylic acid (1-pyridin-2-yl-cyclohexylmethyl)-amide
Inchi Key	BPCFMFDDQQKBBY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C33H34F3N5O3/c34-33(35,36)44-23-13-11-22(12-14-23)39-30(43)41-32(18-15-27-25(20-32)24-8-2-3-9-26(24)40-27)29(42)38-21-31(16-5-1-6-17-31)28-10-4-7-19-37-28/h2-4,7-14,19,40H,1,5-6,15-18,20-21H2,(H,38,42)(H2,39,41,43)
PubChem CID	44334155
ChEMBL	CHEMBL106065
IUPHAR	N/A
BindingDB	50147037
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29399	Neuromedin-B receptor	P28336	NMBR	Homo sapiens (Human)	390

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