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Ligand

NameMetopimazine
Molecular formulaC22H27N3O3S2
IUPAC name1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide
Molecular weight445.596
Hydrogen bond acceptor6
Hydrogen bond donor1
XlogP3.1
Synonyms118285-EP2298765A1
4-Piperidinecarboxamide, 1-(3-(2-(methylsulfonyl)-10H-phenothiazin-10-yl)propyl)-
BDBM179867
CHEMBL398615
ISONIPECOTAMIDE, 1-(3-(2-(METHYLSULFONYL)PHENOTHIAZIN-10-YL)PROPYL)-
[ Show all ]
Inchi KeyBQDBKDMTIJBJLA-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H27N3O3S2/c1-30(27,28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26)
PubChem CID26388
ChEMBLCHEMBL398615
IUPHARN/A
BindingDB179867, 82383
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
30162Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
30163Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
459474D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
459472D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
459473Histamine H1 receptorP35367HRH1Homo sapiens (Human)487

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