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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000622033
Molecular formula	C23H22FN5
IUPAC name	7-(4-fluorophenyl)-4-(4-methylpiperazin-1-yl)-5-phenylpyrrolo[2,3-d]pyrimidine
Molecular weight	387.462
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	4.3
Synonyms	HMS2712L07 STL262712 7-(4-fluorophenyl)-4-(4-methyl-1-piperazinyl)-5-phenylpyrrolo[2,3-d]pyrimidine BDBM96912 MolPort-000-450-387 7-(4-fluorophenyl)-4-(4-methylpiperazin-1-yl)-5-phenylpyrrolo[2,3-d]pyrimidine CHEMBL1490948 SR-01000568231 AC1LU7FB MCULE-5848659044 ZINC1447671 7-(4-fluorophenyl)-4-(4-methylpiperazin-1-yl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidine CCG-199390 Oprea1_396566 7-(4-fluorophenyl)-4-(4-methylpiperazino)-5-phenyl-pyrrolo[2,3-d]pyrimidine cid_1522618 SR-01000568231-1 AKOS002102229 7-(4-fluorophenyl)-4-(4-methylpiperazin-1-yl)-5-phenyl-pyrrolo[2,3-d]pyrimidine SMR000310960 [ Show all ]
Inchi Key	BULMODKVYZUWGQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H22FN5/c1-27-11-13-28(14-12-27)22-21-20(17-5-3-2-4-6-17)15-29(23(21)26-16-25-22)19-9-7-18(24)8-10-19/h2-10,15-16H,11-14H2,1H3
PubChem CID	1522618
ChEMBL	CHEMBL1490948
IUPHAR	N/A
BindingDB	96912
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33165	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
33166	Trace amine-associated receptor 1	Q96RJ0	TAAR1	Homo sapiens (Human)	339

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