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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL331577
Molecular formula	C25H32N2O5
IUPAC name	(2R,3R,4S)-2,4-bis(4-methoxyphenyl)-1-[2-[methyl(propyl)amino]-2-oxoethyl]pyrrolidine-3-carboxylic acid
Molecular weight	440.54
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	0.9
Synonyms	BDBM50056073 (2R,3R,4S)-2,4-Bis-(4-methoxy-phenyl)-1-[(methyl-propyl-carbamoyl)-methyl]-pyrrolidine-3-carboxylic acid
Inchi Key	BVNZXNOMGWQSDJ-JRFVFWCSSA-N
Inchi ID	InChI=1S/C25H32N2O5/c1-5-14-26(2)22(28)16-27-15-21(17-6-10-19(31-3)11-7-17)23(25(29)30)24(27)18-8-12-20(32-4)13-9-18/h6-13,21,23-24H,5,14-16H2,1-4H3,(H,29,30)/t21-,23-,24+/m1/s1
PubChem CID	10813007
ChEMBL	CHEMBL331577
IUPHAR	N/A
BindingDB	50056073
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33906	Endothelin receptor type B	P35463	EDNRB	Sus scrofa (Pig)	443
33905	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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