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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL7917696
Molecular formula	C24H22FN5O2
IUPAC name	[(2R,5R)-5-(8-fluoroquinolin-4-yl)oxy-2-methylpiperidin-1-yl]-[2-(triazol-2-yl)phenyl]methanone
Molecular weight	431.471
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.4
Synonyms	US8710076, E-2 CHEMBL3394842 BDBM120777
Inchi Key	BVUZOFDSUCGTDO-IAGOWNOFSA-N
Inchi ID	InChI=1S/C24H22FN5O2/c1-16-9-10-17(32-22-11-12-26-23-19(22)6-4-7-20(23)25)15-29(16)24(31)18-5-2-3-8-21(18)30-27-13-14-28-30/h2-8,11-14,16-17H,9-10,15H2,1H3/t16-,17-/m1/s1
PubChem CID	46212134
ChEMBL	CHEMBL3394842
IUPHAR	N/A
BindingDB	120777
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
34093	Orexin receptor type 1	P56718	Hcrtr1	Rattus norvegicus (Rat)	416
443002	Orexin receptor type 1	O43613	HCRTR1	Homo sapiens (Human)	425
34094	Orexin receptor type 2	O43614	HCRTR2	Homo sapiens (Human)	444

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