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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2334976
Molecular formula	C23H23N5OS
IUPAC name	(1R,2R)-N-[4-(6-ethylpyridin-2-yl)-3-(2-methylindazol-5-yl)-1,2-thiazol-5-yl]-2-methylcyclopropane-1-carboxamide
Molecular weight	417.531
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.1
Synonyms	BDBM50429655 CHEMBL2365134 (1R,2R)-2-methyl-cyclopropanecarboxylic acid [4-(6-ethyl-pyridin-2-yl)-3-(2-methyl-2H-indazol-5-yl)-isothiazol-5-yl]-amide BWXIPDFABPPPPW-CXAGYDPISA-N SCHEMBL1635768
Inchi Key	BWXIPDFABPPPPW-CXAGYDPISA-N
Inchi ID	InChI=1S/C23H23N5OS/c1-4-16-6-5-7-19(24-16)20-21(14-8-9-18-15(11-14)12-28(3)26-18)27-30-23(20)25-22(29)17-10-13(17)2/h5-9,11-13,17H,4,10H2,1-3H3,(H,25,29)/t13-,17-/m1/s1
PubChem CID	44230992
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50429655
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
34832	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
34833	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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