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Ligand

NameCHEMBL418462
Molecular formulaC13H15ClN2O4
IUPAC name(2R,4R)-4-amino-1-[(2-chlorophenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Molecular weight298.723
Hydrogen bond acceptor6
Hydrogen bond donor3
XlogP-3.9
SynonymsBDBM50071165
SCHEMBL8973329
(2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid
Inchi KeyBXTHDFVMVOKYQK-ZWNOBZJWSA-N
Inchi IDInChI=1S/C13H15ClN2O4/c14-9-4-2-1-3-8(9)6-16-7-13(15,12(19)20)5-10(16)11(17)18/h1-4,10H,5-7,15H2,(H,17,18)(H,19,20)/t10-,13-/m1/s1
PubChem CID44302819
ChEMBLCHEMBL418462
IUPHARN/A
BindingDB50071165
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
35425Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
35426Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872
35423Metabotropic glutamate receptor 3Q14832GRM3Homo sapiens (Human)879
35427Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
35428Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212
35424Metabotropic glutamate receptor 8O00222GRM8Homo sapiens (Human)908

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