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Ligand

NameCHEMBL299454
Molecular formulaC21H30ClN3O
IUPAC name8-[2-[4-(2-chlorophenyl)piperazin-1-yl]ethyl]-8-azaspiro[4.5]decan-9-one
Molecular weight375.941
Hydrogen bond acceptor3
Hydrogen bond donor0
XlogP4.1
Synonyms8-{2-[4-(2-Chloro-phenyl)-piperazin-1-yl]-ethyl}-8-aza-spiro[4.5]decan-7-one
BDBM50143680
Inchi KeyBYHQOSOPNSLUAD-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H30ClN3O/c22-18-5-1-2-6-19(18)24-14-11-23(12-15-24)13-16-25-10-9-21(17-20(25)26)7-3-4-8-21/h1-2,5-6H,3-4,7-17H2
PubChem CID11234230
ChEMBLCHEMBL299454
IUPHARN/A
BindingDB50143680
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
357985-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
35797Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
35801Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
35799Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
35800Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561

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