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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL55460
Molecular formula	C20H27Cl2N3O2
IUPAC name	8-[2-[2-(2,5-dichloroanilino)ethyl-methylamino]ethyl]-8-azaspiro[4.5]decane-7,9-dione
Molecular weight	412.355
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.2
Synonyms	8-(2-{[2-(2,5-Dichloro-phenylamino)-ethyl]-methyl-amino}-ethyl)-8-aza-spiro[4.5]decane-7,9-dione BDBM50143710
Inchi Key	CAFBNEJZNQABOY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H27Cl2N3O2/c1-24(9-8-23-17-12-15(21)4-5-16(17)22)10-11-25-18(26)13-20(14-19(25)27)6-2-3-7-20/h4-5,12,23H,2-3,6-11,13-14H2,1H3
PubChem CID	11350440
ChEMBL	CHEMBL55460
IUPHAR	N/A
BindingDB	50143710
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
37110	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
37111	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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