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Ligand

Nametriprolidine
Molecular formulaC19H22N2
IUPAC name2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine
Molecular weight278.399
Hydrogen bond acceptor2
Hydrogen bond donor0
XlogP3.9
SynonymsNCGC00024714-03
(E)-2-(1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)pyridine
Prestwick2_000262
2-(3-Pyrrolidin-1-yl-1-p-tolyl-propenyl)-pyridine
Spectrum5_001467
[ Show all ]
Inchi KeyCBEQULMOCCWAQT-WOJGMQOQSA-N
Inchi IDInChI=1S/C19H22N2/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21/h2-3,6-12H,4-5,13-15H2,1H3/b18-11+
PubChem CID5282443
ChEMBLCHEMBL855
IUPHAR1228
BindingDB50292411
DrugBankDB00427

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
37806D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
37802Histamine H1 receptorP31389HRH1Cavia porcellus (Guinea pig)488
37803Histamine H1 receptorP31390Hrh1Rattus norvegicus (Rat)486
37804Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
37805Histamine H2 receptorP47747HRH2Cavia porcellus (Guinea pig)359

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