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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	L-765314
Molecular formula	C27H34N6O5
IUPAC name	benzyl (2S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate
Molecular weight	522.606
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	3.1
Synonyms	1-piperazinecarboxylic acid, 4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-2-[[(1,1-dimethylethyl)amino]carbonyl]-, phenylmethyl ester, (S)- benzyl (S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate NCGC00094440-01 CHEMBL19476 SCHEMBL7820114 (S)-1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(benzyloxy)carbonyl]-3-(1,1-dimethylethylamino)carbonyl piperazine BDBM50063907 GTPL506 Lopac-L-3040 189349-50-6 CGWOIDCAGBKOQL-FQEVSTJZSA-N NCGC00165822-01 AC1O7G4J CS-0021271 ZINC84638100 (S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-tert-butylcarbamoyl-piperazine-1-carboxylic acid benzyl ester benzyl (2S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate HY-101385 NCGC00015604-01 phenylmethyl (2S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate (2S)-2alpha-(tert-Butylcarbamoyl)-4-(4-amino-6,7-dimethoxyquinazoline-2-yl)piperazine-1-carboxylic acid benzyl ester AKOS032960320 D09ZUW [ Show all ]
Inchi Key	CGWOIDCAGBKOQL-FQEVSTJZSA-N
Inchi ID	InChI=1S/C27H34N6O5/c1-27(2,3)31-24(34)20-15-32(11-12-33(20)26(35)38-16-17-9-7-6-8-10-17)25-29-19-14-22(37-5)21(36-4)13-18(19)23(28)30-25/h6-10,13-14,20H,11-12,15-16H2,1-5H3,(H,31,34)(H2,28,29,30)/t20-/m0/s1
PubChem CID	6603904
ChEMBL	CHEMBL19476
IUPHAR	506
BindingDB	50063907
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
41694	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
41698	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
41690	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
41695	Alpha-1B adrenergic receptor	P15823	Adra1b	Rattus norvegicus (Rat)	515
41696	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
41697	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
41691	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
41692	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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