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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL18357227
Molecular formula	C28H28ClNO4S
IUPAC name	4-[3-[(2R)-2-[(E)-3-[5-(4-chloro-2-methylphenyl)thiophen-2-yl]-3-hydroxyprop-1-enyl]-5-oxopyrrolidin-1-yl]propyl]benzoic acid
Molecular weight	510.045
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.4
Synonyms	BDBM202460 US9540357, example 33 US9540357, example 32
Inchi Key	CHEGULSFMGKALD-RRPJXJBHSA-N
Inchi ID	InChI=1S/C28H28ClNO4S/c1-18-17-21(29)8-11-23(18)25-13-14-26(35-25)24(31)12-9-22-10-15-27(32)30(22)16-2-3-19-4-6-20(7-5-19)28(33)34/h4-9,11-14,17,22,24,31H,2-3,10,15-16H2,1H3,(H,33,34)/b12-9+/t22-,24?/m0/s1
PubChem CID	124170688
ChEMBL	N/A
IUPHAR	N/A
BindingDB	202460
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558545	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
558546	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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