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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL256424
Molecular formula	C29H24FN5O2
IUPAC name	8-[2-(4-fluorophenyl)ethynyl]-7-[2-hydroxyethyl(methyl)amino]-4-(3-imidazol-1-ylphenyl)-1,3-dihydro-1,5-benzodiazepin-2-one
Molecular weight	493.542
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.7
Synonyms	BDBM50372874 SCHEMBL7172578
Inchi Key	CHIPHPDGPBIINM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H24FN5O2/c1-34(13-14-36)28-17-27-26(16-22(28)8-5-20-6-9-23(30)10-7-20)33-29(37)18-25(32-27)21-3-2-4-24(15-21)35-12-11-31-19-35/h2-4,6-7,9-12,15-17,19,36H,13-14,18H2,1H3,(H,33,37)
PubChem CID	22448874
ChEMBL	CHEMBL256424
IUPHAR	N/A
BindingDB	50372874
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
42026	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558547	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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