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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL484578
Molecular formula	C20H21ClN4O
IUPAC name	2-[[(1R,5S)-6-[(3-chlorophenoxy)methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methyl]-1-methylimidazo[4,5-c]pyridine
Molecular weight	368.865
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.9
Synonyms	2-(((1R,5S)-6-((3-chlorophenoxy)methyl)-3-aza-bicyclo[3.1.0]hexan-3-yl)methyl)-1-methyl-1H-imidazo[4,5-c]pyridine BDBM50274144
Inchi Key	CIFLTVMHVNJKRH-SJPCQFCGSA-N
Inchi ID	InChI=1S/C20H21ClN4O/c1-24-19-5-6-22-8-18(19)23-20(24)11-25-9-15-16(10-25)17(15)12-26-14-4-2-3-13(21)7-14/h2-8,15-17H,9-12H2,1H3/t15-,16+,17?
PubChem CID	25050845
ChEMBL	CHEMBL484578
IUPHAR	N/A
BindingDB	50274144
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
42652	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558578	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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