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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000587237
Molecular formula	C20H18N2O4
IUPAC name	(5E)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-1-(4-propan-2-ylphenyl)-1,3-diazinane-2,4,6-trione
Molecular weight	350.374
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.6
Synonyms	(5E)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-6-hydroxy-3-[4-(propan-2-yl)phenyl]pyrimidine-2,4(3H,5H)-dione AKOS005544156 MolPort-002-567-471 (5E)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-1-(4-propan-2-ylphenyl)-1,3-diazinane-2,4,6-trione CHEMBL1509980 STK608858 AC1LZH7U (5E)-5-[(E)-3-(2-furanyl)prop-2-enylidene]-1-(4-propan-2-ylphenyl)-1,3-diazinane-2,4,6-trione BDBM79560 SMR000211311 (5Z)-5-[(E)-3-(2-furyl)prop-2-enylidene]-1-p-cumenyl-barbituric acid cid_1922630 ZINC8914163 (5E)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-1-[4-(propan-2-yl)phenyl]pyrimidine-2,4,6(1H,3H,5H)-trione AKOS000323973 MolPort-000-829-099 (5E)-5-[(E)-3-(2-furyl)prop-2-enylidene]-1-p-cumenyl-barbituric acid STK176474 5-[(E)-3-Furan-2-yl-prop-2-en-(E)-ylidene]-1-(4-isopropyl-phenyl)-pyrimidine-2,4,6-trione HMS2639M14 [ Show all ]
Inchi Key	CJOKZQXLSSIEPY-GOBGXLLKSA-N
Inchi ID	InChI=1S/C20H18N2O4/c1-13(2)14-8-10-15(11-9-14)22-19(24)17(18(23)21-20(22)25)7-3-5-16-6-4-12-26-16/h3-13H,1-2H3,(H,21,23,25)/b5-3+,17-7+
PubChem CID	1922630
ChEMBL	CHEMBL1509980
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
43561	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
43559	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
43560	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
468256	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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