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Ligand

NameCHEMBL573284
Molecular formulaC18H21N5O2
IUPAC name4-[(1R)-1-cyclopropylethyl]-6-[(6-methoxy-2,5-dimethylpyridin-3-yl)amino]-5-oxopyrazine-2-carbonitrile
Molecular weight339.399
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP1.9
SynonymsBDBM50300141
(R)-4-(1-Cyclopropylethyl)-6-(6-methoxy-2,5-dimethylpyridin-3-ylamino)-5-oxo-4,5-dihydropyrazine-2-carbonitrile
Inchi KeyCLRRTXABLKAYGU-GFCCVEGCSA-N
Inchi IDInChI=1S/C18H21N5O2/c1-10-7-15(11(2)20-17(10)25-4)22-16-18(24)23(9-14(8-19)21-16)12(3)13-5-6-13/h7,9,12-13H,5-6H2,1-4H3,(H,21,22)/t12-/m1/s1
PubChem CID44596702
ChEMBLCHEMBL573284
IUPHARN/A
BindingDB50300141
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 1
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GLASS IDNameUniProtGeneSpeciesLength
44940Corticotropin-releasing factor receptor 1P35353Crhr1Rattus norvegicus (Rat)415

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