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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL98299
Molecular formula	C27H30FN7O
IUPAC name	1-[2-[4-[1-(4-fluorophenyl)-5-(2-methyl-1,2,4-triazol-3-yl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight	487.583
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.2
Synonyms	BDBM50122821 1-(2-{4-[1-(4-Fluoro-phenyl)-5-(2-methyl-2H-[1,2,4]triazol-3-yl)-1H-indol-3-yl]-piperidin-1-yl}-ethyl)-imidazolidin-2-one
Inchi Key	CLSRMUGSDHADPG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H30FN7O/c1-32-26(30-18-31-32)20-2-7-25-23(16-20)24(17-35(25)22-5-3-21(28)4-6-22)19-8-11-33(12-9-19)14-15-34-13-10-29-27(34)36/h2-7,16-19H,8-15H2,1H3,(H,29,36)
PubChem CID	11092142
ChEMBL	CHEMBL98299
IUPHAR	N/A
BindingDB	50122821
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
44973	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
44971	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
44972	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
44969	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
44970	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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