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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL477375
Molecular formula	C21H21ClFN3O
IUPAC name	2-[[(1S,5R)-6-[(4-chloro-2-fluorophenoxy)methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methyl]-1-methylbenzimidazole
Molecular weight	385.867
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.0
Synonyms	2-(((1R,5S)-6-((4-chloro-2-fluorophenoxy)methyl)-3-aza-bicyclo[3.1.0]hexan-3-yl)methyl)-1-methyl-1H-benzo[d]imidazole BDBM50263391
Inchi Key	COZAYWMOVJHAOV-XYPWUTKMSA-N
Inchi ID	InChI=1S/C21H21ClFN3O/c1-25-19-5-3-2-4-18(19)24-21(25)11-26-9-14-15(10-26)16(14)12-27-20-7-6-13(22)8-17(20)23/h2-8,14-16H,9-12H2,1H3/t14-,15+,16?
PubChem CID	44578948
ChEMBL	CHEMBL477375
IUPHAR	N/A
BindingDB	50263391
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
47139	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
558732	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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